Nature's own marvelous nanoscale machines include motors that spin bacterial flagella at up to 1000 revolutions per second and polymerases that step along DNA and RNA to facilitate the flow of genetic information. Block, along with other Stanford researchers such as Professors W. E. Moerner (Chemistry) and Steve Chu (Physics), are studying Nature's machines through single molecule science. This young field is devoted to following molecules one at a time rather than observing their averaged behavior, as has been done traditionally. To understand why average properties may obscure molecular behavior, "Consider a ship traveling from New York to San Francisco," says Block. "If it's small enough, it will travel down into the Caribbean and go across the Panama Canal and then back up to San Francisco. If it's a big oil tanker, it won't fit through the Panama Canal; it's got to go all the way around Cape Horn. But the average path of a ship traveling from New York to San Francisco wo
 uld probably come out somewhere in the middle of the Amazon where there is in fact no route at all!"








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Electronics: Building Chips in 3-D Dr. Krishna Saraswat, Electronic Engineering; Dr. Chris Chidsey, Chemistry
All over campus, Stanford has eagerly embraced the "grand challenges" of nanotechnology. Just this April, the Stanford Nanofabrication Facility (SNF) hosted an open house to celebrate its selection to be part of the National Science Foundation-sponsored National Nanotechnology Infrastructure Network sprawling across thirteen universities nationwide. Along with the new Nanocharacterization Laboratory expanding the SNF, the nearly finished Manoharan lab that Stanford students bike past on the way to physics lab embodies the prominent place nanotechnology has in Stanford research for years to come. Specifically, the Manoharan lab is equipped to manipulate matter on an atomic level. Here's a cross-section of nanotechnology research currently being pursued at Stanford: